Research Archive - Page 5 of 8

Research

A selection of links to recent research papers available online and may be free to access.

The conclusions are those of the authors and do not necessarily represent the views of the WMSoc.

Effects of early biofilm formation on water quality during commissioning of new polyethylene pipes

Highlights Mature biofilms are considered beneficial to non-chlorinated Danish drinking water distribution systems, as they increase the microbiological stability of the water. During commissioning of new pipes, biofilms start developing on the new pipe wall, and are influenced by factors such as water quality, pipe material, flow velocity and presence of biofilm upstream. The early… Read more »

Impact of prolonged hotel closures during the COVID-19 pandemic on Legionella infection risks

Highlights There are very few field studies comparing the level of Legionella colonisation in buildings before and after the pandemic lockdowns. This study analysed a group of hotels that experienced prolonged closures in 2020 due to the COVID-19 pandemic. Legionella spp. were analysed by standard culture, immediately after reopening, from the domestic water distribution systems of 73… Read more »

Legionella bononiensis sp. nov., isolated from a hotel water distribution system in northern Italy – Microbiology Society (microbiologyresearch.org)

Highlights Legionella-like isolates were isolated from a hotel water distribution system in Italy. Isolates were Gram-negative, rod-shaped and able to grow at 32–37 °C on buffered charcoal–yeast extract agar. Genetic analysis showed a close relationship with L. quateirensis The results obtained confirm the status of an independent species. The name proposed for this species is Legionella bononiensis nov…. Read more »

Genomic characterization and assessment of pathogenic potential of Legionella spp. isolates from environmental monitoring – PubMed (nih.gov)

Highlights Over several years of molecular and genome-based monitoring, Legionella isolates from different geographical locations were collected and 39 of them were sequenced. In addition they were typed by standard culture and MALDI-TOF. Four potential new species in the Legionella genus were identified, which still need to be characterised fully. This study assists in the… Read more »

Predicting Legionella contamination in cooling towers and evaporative condensers from microbiological and physicochemical parameters – ScienceDirect

Highlights The main aim of this study was to assess the risk of Legionella colonisation in cooling towers (CT) and evaporative condensers (EC) in Barcelona, Spain. Legionella was analysed in 789 samples collected from 127 CT and EC in 46 companies in Catalonia from 2002 to 2019. Legionella was isolated in 8.49% of the 789… Read more »

Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin – Nature Catalysis

Highlights The peptide antibiotic albicidin is a DNA topoisomerase inhibitor with low-nanomolar bactericidal activity towards fluoroquinolone-resistant Gram-negative pathogens. However, its mode of action is poorly understood. Albicidin employs a dual binding mechanism where one end of the molecule obstructs the crucial gyrase dimer interface, while the other intercalates between the fragments of cleaved DNA substrate…. Read more »

Vehicle Windshield Wiper Fluid as Potential Source of Sporadic Legionnaires’ Disease in Commercial Truck Drivers

Abstract Sporadic Legionnaires’ disease is frequently detected in commercial truck drivers. We report 2 sporadic cases of this disease in Barcelona, Spain, that occurred during December 2019 and September 2020. Laboratory findings were consistent with windshield wiper fluid without added screen wash as a possible source of infection for both cases. LINK TO PAPER… Read more »

Epidemiological analysis of Legionnaires’ disease in Scotland: a genomic study

Highlights: Whole-genome sequencing (WGS) can be applied to trace environmental origins of L pneumophila infections. This study explored the evolutionary and epidemiological relationships in a 36-year Scottish L pneumophila reference isolate collection. The data revealed the existence of previously undetected endemic clones of L pneumophila that existed for many years in hospital, community, and travel-associated environments. In light of these findings,… Read more »

Cell-free production of personalized therapeutic phages targeting multidrug-resistant bacteria

Highlights: Bacteriophages are potent therapeutics against biohazardous bacteria, which rapidly develop multidrug resistance. Routine administration of phage therapy is hampered by a lack of rapid production, safe bioengineering, and detailed characterization of phages. A cell-free platform has been developed for a broad spectrum of phages and which produced effective doses against enteroaggregative Escherichia coli (EAEC),… Read more »

Drugs of abuse in tap water from eight European countries: Determination by use of supramolecular solvents and tentative evaluation of risks to human health – PubMed (nih.gov)

Muñiz-Bustamante L, Caballero-Casero N, Rubio S. Drugs of abuse in tap water from eight European countries: Determination by use of supramolecular solvents and tentative evaluation of risks to human health. Environ Int. 2022 Jun;164:107281. doi: 10.1016/j.envint.2022.107281. Epub 2022 May 6. PMID: 35561596. Highlights Recent research findings have confirmed the presence of illicit drugs in… Read more »

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